It's Bob's Burgers grand re-re-re opening, but the festivities are delayed by the health inspector. Louise, wanting to "up the ante" at show & tell, tells the class her dad, Bob, uses human remains in the burgers at Bob's Burgers.
Bob re-re-re-opens the restaurant, after a struggle of disasters, for Labor Day weekend. While being reopened, Hugo, the health inspector, visits the restaurant after seeing Gene spilling burger samples on the ground and re-serving them. He writes up his book and suspects them for serving human flesh to the customers due to Louise making up the rumor in her class. Soon, it is revealed that Linda was once engaged to Hugo, making Bob jealous. The new sign setup by Hugo throws customers away. In spite of Bob's claims that the rumor is false, the situation gets even worse when one of Gene's antics ends with a body from the crematorium turning up at the restaurant. Bob finally decides to stand up against the crowds outside, and while he initially appears to be succeeding, he ends up coming off as a supporter of cannibalism.
As the public continue to berate him, Bob sobs to Linda that he's a failure and she would have been better off had she stayed with Hugo, who she earlier admitted was a better kisser than Bob. However, Linda tells Bob that she left with Bob because he had a dream for the future, whereas Hugo was nothing but a lonely man who never had anything going for him. Louise also apologize for making up the rumor.
Later on, a bus of exotic eaters are attracted to Bob's Burgers after hearing about the human flesh incident, and Bob charges $50 for each burger. Ron, Hugo's assistant, tells Bob that they found no human flesh, although Bob attempts to shoo Ron away and let the customers eat. In the end, Bob has a successful amount of money and takes his family to the amusement park down the road.